Journal Overview

CPT: Pharmacometrics & Systems Pharmacology (PSP) is an official open access journal of the American Society for Clinical Pharmacology and Therapeutics (ASCPT) and International Society of Pharmacometrics (ISoP)

Featured in CPT: Pharmacometrics & Systems Pharmacology

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CPT: Pharmacometrics & Systems Pharmacology – Inception, Maturation, and Future Vision

New Cover for CPT:PSP.

Identification of high-dimensional omics-derived predictors for tumor growth dynamics using machine learning and pharmacometric modeling

A schematic visualization of the proposed two-step approach.

Scientific and regulatory evaluation of mechanistic in silico drug and disease models in drug development: Building model credibility

In silico Model Process flowchart.

Browse Articles

Open access

Skipping a pillar does not make for strong foundations: Pharmacokinetic-pharmacodynamic reasoning behind the shape of dose–response relationships in oncology

James W. T. Yates, Hitesh B. Mistry, 
  •  28 September 2023
Open access

Issue Information

  •  1183-1186
  •  19 September 2023
First page image
Open access

Mixed effects modeling of radiotherapy in combination with immune checkpoint blockade or inhibitors of the DNA damage response pathway

David Hodson, Hitesh Mistry, Sofia Guzzetti, Michael Davies, Anna Staniszewska, Paul Farrington, Elaine Cadogan, James Yates, Leon Aarons, Kayode Ogungbenro, 
  •  18 September 2023
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Open access

Pharmacokinetics of Monoclonal Antibodies

Josiah T. Ryman, Bernd Meibohm, 
  •  576-588
  •  27 June 2017
Open access

Application of ggplot2 to Pharmacometric Graphics

K Ito, D Murphy, 
  •  1-16
  •  16 October 2013
Open access

Basic Concepts in Population Modeling, Simulation, and Model‐Based Drug Development—Part 2: Introduction to Pharmacokinetic Modeling Methods

DR Mould, RN Upton, 
  •  1-14
  •  17 April 2013
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Open access

Tutorial on Model Selection and Validation of Model Input into Precision Dosing Software for Model‐Informed Precision Dosing

Zachary L. Taylor, Ethan A. Poweleit, Kelli Paice, Katherine M. Somers, Kathryn Pavia, Alexander A. Vinks, Nieko Punt, Tomoyuki Mizuno, Sonya Tang Girdwood, 
Open access

A Markov model of fibrosis development in Non‐Alcoholic Fatty Liver Disease predicts fibrosis progression in clinical cohorts

Jane Knöchel, Linnéa Bergenholm, Eman Ibrahim, Stergios Kechagias, Sara Hansson, Mathias Liljeblad, Patrik Nasr, Björn Carlsson, Mattias Ekstedt, Sebastian Ueckert, 
Open access

Physiologically Based Mechanistic Insight into Differential Risk of Valproate Hepatotoxicity between Children and Adults: A Focus on Ontogeny Impact

Yu-Ting Huang, Yen-Ming Huang, Fan-Lu Kung, Chun-June Lin, Tun Jao, Yunn-Fang Ho, 
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