Journal Overview

Clinical Pharmacology & Therapeutics (CPT) is the flagship journal of the American Society for Clinical Pharmacology and Therapeutics (ASCPT).

Featured in Clinical Pharmacology & Therapeutics

Skip slideshow

Association Between FIASMAs and Reduced Risk of Intubation or Death in Individuals Hospitalized for Severe COVID-19: An Observational Multicenter Study

Biological mechanisms proposed by Carpinteiro et al. underlying the potential inhibition by Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) of cell infection with severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2).

Cost-Sharing Increase, Medication Adherence, and Hospitalizations in Schizophrenia Patients: A Natural Experiment

Patient selection flowchart. SCZ, schizophrenia.

When Can Nonrandomized Studies Support Valid Inference Regarding Effectiveness or Safety of New Medical Treatments?

Valid inference on medication effects from nonrandomized studies. RCT, randomized controlled trial.

Browse Articles

free access

Issue Information

  •  197-202
  •  24 January 2023
First page image

In This Issue

  •  205-206
  •  24 January 2023
No abstract is available for this article.

Highlights

  •  210-211
  •  24 January 2023
No abstract is available for this article.

ASCPT NEWS

  •  212-217
  •  24 January 2023
First page image
free access

Could Metabolomics Be the Key to Unlocking Precision Dosing in the Clinic?

Joseph F. Standing, 
  •  207-209
  •  24 January 2023
No abstract is available for this article.
more >
free access

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

JK Hicks, JR Bishop, K Sangkuhl, DJ Müller, Y Ji, SG Leckband, JS Leeder, RL Graham, DL Chiulli, A LLerena, TC Skaar, SA Scott, JC Stingl, TE Klein, KE Caudle, A Gaedigk, 
  •  127-134
  •  13 May 2015
free access

Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update

Mary V. Relling, Matthias Schwab, Michelle Whirl-Carrillo, Guilherme Suarez-Kurtz, Ching-Hon Pui, Charles M. Stein, Ann M. Moyer, William E. Evans, Teri E. Klein, Federico Guillermo Antillon-Klussmann, Kelly E. Caudle, Motohiro Kato, Allen E.J. Yeoh, Kjeld Schmiegelow, Jun J. Yang, 
  •  1095-1105
  •  17 November 2018
free access

Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update

JK Hicks, K Sangkuhl, JJ Swen, VL Ellingrod, DJ Müller, K Shimoda, JR Bishop, ED Kharasch, TC Skaar, A Gaedigk, HM Dunnenberger, TE Klein, KE Caudle, JC Stingl, 
  •  37-44
  •  20 December 2016
First page image
More >

ABCB1 gene variants and Antidepressant Treatment Outcomes: A Systematic Review and Meta-analysis including results from the CAN-BIND-1 Study

Leen Magarbeh, Claudia Hassel, Maximilian Choi, Farhana Islam, Victoria S. Marshe, Clement C. Zai, Rayyan Zuberi, Roseann S. Gammal, Xiaoyu Men, Maike Scherf-Clavel, Dietmar Enko, Benicio N. Frey, Roumen Milev, Claudio N. Soares, Sagar V. Parikh, Franca Placenza, Stephen C. Strother, Stefanie Hassel, Valerie H. Taylor, Francesco Leri, Pierre Blier, Faranak Farzan, Raymond W. Lam, Gustavo Turecki, Jane A. Foster, Susan Rotzinger, Stefan Kloiber, James L. Kennedy, Sidney H. Kennedy, Chad A. Bousman, Daniel J. Müller, 

Mitigating Drug–Target–Drug Complexes in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Switch C5 Inhibitors

Jun-ichi Nishimura, Antoine Soubret, Noriko Arase, Simon Buatois, Masaki Hotta, Jean-Eric Charoin, Yoshikazu Ito, Sasha Sreckovic, Hiroyuki Takamori, Christoph Bucher, Yasutaka Ueda, Jules Hernández-Sánchez, Keisuke Gotanda, Gregor Jordan, Kenji Shinomiya, Julia Ramos, Jin Seok Kim, Jens Panse, Régis Peffault de Latour, Alexander Röth, Eiichi Morii, Hubert Schrezenmeier, Yoshitaka Isaka, Simona Sica, Yuzuru Kanakura, Sung-Soo Yoon, Taroh Kinoshita, Ido Paz-Priel, Alexandre Sostelly, 
Open access

Characterizing granulocytopenia associated with thiamazole in patients with hyperthyroidism based on real-world data from the MID-NET® in Japan

Yuki Kinoshita, Kazuhiro Kajiyama, Chieko Ishiguro, Takahiro Nonaka, Ryota Kimura, Yuki Kikuchi, Naoya Horiuchi, Toyotaka Iguchi, Yoshiaki Uyama, 
more >

Latest news

More news >