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Clinical Pharmacology & Therapeutics (CPT) is the flagship journal of the American Society for Clinical Pharmacology and Therapeutics (ASCPT).
Featured in Clinical Pharmacology & Therapeutics
Browse Articles
Population Pharmacokinetics and Exposure–Response Analysis for the CTLA‐4 Inhibitor Tremelimumab in Metastatic NSCLC Patients in the Phase III POSEIDON Study
Jimmy Zhijian He, Vincent Duval, Petra Jauslin, Antonio Gonçalves, Aburough Abegesah, Chunling Fan, KyoungSoo Lim, Xuyang Song, Cecil Chen, Xiaojin Shi, Helen Mann, Lee Krug, Song Ren, Alex Phipps, Megan Gibbs, Diansong Zhou,
-  30 September 2023
Determination and Confirmation of Recommended Ph2 Dose of Amivantamab in Epidermal Growth Factor Receptor Exon 20 Insertion Non‐Small Cell Lung Cancer
Nahor Haddish-Berhane, Yaming Su, Alberto Russu, Meena Thayu, Roland E. Knoblauch, Jaydeep Mehta, John Xie, Eric Gibbs, Yu-Nien Sun, Honghui Zhou,
-  30 September 2023
Model‐informed selection of the recommended phase 3 dose of the inhibitor of apoptosis protein inhibitor, xevinapant, in combination with cisplatin and concurrent radiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck
Yulia Vugmeyster, Abhigyan Ravula, Elisabeth Rouits, Paul Matthias Diderichsen, Huub Jan Kleijn, Andre Koenig, XiaoZhe Wang, Andreas Schroeder, Kosalaram Goteti, Karthik Venkatakrishnan,
-  30 September 2023
Individualized use of 6‐mercaptopurine in Chinese children with ALL: A multicenter randomized controlled trial
Yue Zhou, Li Wang, Li-Rong Sun, Li Zhang, Hong-Mei Wang, Xi-Ting Liu, Fan Yang, Ke-Liang Wu, Yu-Li Liang, Bei-Bei Zhao, Yong Zhuang, Jin-Qiu Fu, Chao Song, Yun Li, Ling-Zhen Wang, Hui-Juan Xu, Yan Gu, John van den Anker, Xiu-Li Ju, Xiao-Fan Zhu, Wei Zhao,
-  27 September 2023
free access
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors
JK Hicks, JR Bishop, K Sangkuhl, DJ Müller, Y Ji, SG Leckband, JS Leeder, RL Graham, DL Chiulli, A LLerena, TC Skaar, SA Scott, JC Stingl, TE Klein, KE Caudle, A Gaedigk,
-  127-134
-  13 May 2015
free access
Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update
Mary V. Relling, Matthias Schwab, Michelle Whirl-Carrillo, Guilherme Suarez-Kurtz, Ching-Hon Pui, Charles M. Stein, Ann M. Moyer, William E. Evans, Teri E. Klein, Federico Guillermo Antillon-Klussmann, Kelly E. Caudle, Motohiro Kato, Allen E.J. Yeoh, Kjeld Schmiegelow, Jun J. Yang,
-  1095-1105
-  17 November 2018
free access
Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update
JK Hicks, K Sangkuhl, JJ Swen, VL Ellingrod, DJ Müller, K Shimoda, JR Bishop, ED Kharasch, TC Skaar, A Gaedigk, HM Dunnenberger, TE Klein, KE Caudle, JC Stingl,
-  37-44
-  20 December 2016

Population Pharmacokinetics and Exposure–Response Analysis for the CTLA‐4 Inhibitor Tremelimumab in Metastatic NSCLC Patients in the Phase III POSEIDON Study
Jimmy Zhijian He, Vincent Duval, Petra Jauslin, Antonio Gonçalves, Aburough Abegesah, Chunling Fan, KyoungSoo Lim, Xuyang Song, Cecil Chen, Xiaojin Shi, Helen Mann, Lee Krug, Song Ren, Alex Phipps, Megan Gibbs, Diansong Zhou,
- Clinical Pharmacology & Therapeutics
-  30 September 2023
Determination and Confirmation of Recommended Ph2 Dose of Amivantamab in Epidermal Growth Factor Receptor Exon 20 Insertion Non‐Small Cell Lung Cancer
Nahor Haddish-Berhane, Yaming Su, Alberto Russu, Meena Thayu, Roland E. Knoblauch, Jaydeep Mehta, John Xie, Eric Gibbs, Yu-Nien Sun, Honghui Zhou,
- Clinical Pharmacology & Therapeutics
-  30 September 2023
Model‐informed selection of the recommended phase 3 dose of the inhibitor of apoptosis protein inhibitor, xevinapant, in combination with cisplatin and concurrent radiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck
Yulia Vugmeyster, Abhigyan Ravula, Elisabeth Rouits, Paul Matthias Diderichsen, Huub Jan Kleijn, Andre Koenig, XiaoZhe Wang, Andreas Schroeder, Kosalaram Goteti, Karthik Venkatakrishnan,
- Clinical Pharmacology & Therapeutics
-  30 September 2023