Journal Overview

Clinical Pharmacology & Therapeutics (CPT) is the flagship journal of the American Society for Clinical Pharmacology and Therapeutics (ASCPT).

Featured in Clinical Pharmacology & Therapeutics

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Association Between FIASMAs and Reduced Risk of Intubation or Death in Individuals Hospitalized for Severe COVID-19: An Observational Multicenter Study

Biological mechanisms proposed by Carpinteiro et al. underlying the potential inhibition by Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) of cell infection with severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2).

Cost-Sharing Increase, Medication Adherence, and Hospitalizations in Schizophrenia Patients: A Natural Experiment

Patient selection flowchart. SCZ, schizophrenia.

When Can Nonrandomized Studies Support Valid Inference Regarding Effectiveness or Safety of New Medical Treatments?

Valid inference on medication effects from nonrandomized studies. RCT, randomized controlled trial.

Browse Articles

ISABELA studies: plasma exposure and target engagement do not explain the lack of efficacy of ziritaxestat in patients with IPF

Amit Taneja, Garrit Jentsch, Stéphane Delage, Matthew J Randall, Bernt van den Blink, Yasmina Bauer, Florence Namour, 
  •  10 December 2023

Highlights

  •  8 December 2023
No abstract is available for this article.

Challenging the Norm: A Multidisciplinary Perspective on Intravenous to Subcutaneous Bridging Strategies for Biologics

Sihem Ait-Oudhia, Yow-Ming Wang, Anne-Gaelle Dosne, Amit Roy, Jin Y. Jin, Jun Shen, Leonid Kagan, Flora T. Musuamba, Lucia Zhang, Shinichi Kijima, Marc R Gastonguay, Daniele Ouellet, 
  •  8 December 2023

Quantitative Systems Toxicology Modeling Informed Safe Dose Selection of Emvododstat in Acute Myeloid Leukemia Patients

Kyunghee Yang, Ronald Kong, Robert Spiegel, John D. Baird, Kylie O’Keefe, Brett A Howell, Paul B Watkins, 
  •  8 December 2023

Drug‐induced Acute Pancreatitis: A Real‐world Pharmacovigilance Study Using the FDA Adverse Event Reporting System Database

Dongxuan Li, Hongli Wang, Chunmeng Qin, Dan Du, Yalan Wang, Qian Du, Songqing Liu, 
  •  8 December 2023
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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

JK Hicks, JR Bishop, K Sangkuhl, DJ Müller, Y Ji, SG Leckband, JS Leeder, RL Graham, DL Chiulli, A LLerena, TC Skaar, SA Scott, JC Stingl, TE Klein, KE Caudle, A Gaedigk, 
  •  127-134
  •  13 May 2015
free access

Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update

Mary V. Relling, Matthias Schwab, Michelle Whirl-Carrillo, Guilherme Suarez-Kurtz, Ching-Hon Pui, Charles M. Stein, Ann M. Moyer, William E. Evans, Teri E. Klein, Federico Guillermo Antillon-Klussmann, Kelly E. Caudle, Motohiro Kato, Allen E.J. Yeoh, Kjeld Schmiegelow, Jun J. Yang, 
  •  1095-1105
  •  17 November 2018
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Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update

JK Hicks, K Sangkuhl, JJ Swen, VL Ellingrod, DJ Müller, K Shimoda, JR Bishop, ED Kharasch, TC Skaar, A Gaedigk, HM Dunnenberger, TE Klein, KE Caudle, JC Stingl, 
  •  37-44
  •  20 December 2016
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ISABELA studies: plasma exposure and target engagement do not explain the lack of efficacy of ziritaxestat in patients with IPF

Amit Taneja, Garrit Jentsch, Stéphane Delage, Matthew J Randall, Bernt van den Blink, Yasmina Bauer, Florence Namour, 

Challenging the Norm: A Multidisciplinary Perspective on Intravenous to Subcutaneous Bridging Strategies for Biologics

Sihem Ait-Oudhia, Yow-Ming Wang, Anne-Gaelle Dosne, Amit Roy, Jin Y. Jin, Jun Shen, Leonid Kagan, Flora T. Musuamba, Lucia Zhang, Shinichi Kijima, Marc R Gastonguay, Daniele Ouellet, 

Quantitative Systems Toxicology Modeling Informed Safe Dose Selection of Emvododstat in Acute Myeloid Leukemia Patients

Kyunghee Yang, Ronald Kong, Robert Spiegel, John D. Baird, Kylie O’Keefe, Brett A Howell, Paul B Watkins, 
More articles

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