Journal Overview

Clinical Pharmacology & Therapeutics (CPT) is the flagship journal of the American Society for Clinical Pharmacology and Therapeutics (ASCPT).

Featured in Clinical Pharmacology & Therapeutics

Skip slideshow

Association Between FIASMAs and Reduced Risk of Intubation or Death in Individuals Hospitalized for Severe COVID-19: An Observational Multicenter Study

Biological mechanisms proposed by Carpinteiro et al. underlying the potential inhibition by Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) of cell infection with severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2).

Cost-Sharing Increase, Medication Adherence, and Hospitalizations in Schizophrenia Patients: A Natural Experiment

Patient selection flowchart. SCZ, schizophrenia.

When Can Nonrandomized Studies Support Valid Inference Regarding Effectiveness or Safety of New Medical Treatments?

Valid inference on medication effects from nonrandomized studies. RCT, randomized controlled trial.

Browse Articles

CAR T‐cell therapy for multiple myeloma: A clinical practice‐oriented review

Norah Layla Sadek MD, Bruno Almeida Costa MD, Karthik Nath MBBS, PhD, Sham Mailankody MBBS, 
  •  26 September 2023

Characterization of the US Food and Drug Administration Post‐Marketing Commitments and Requirements for Pregnancy and Lactation

Charul Avachat, Islam R. Younis, Angela K. Birnbaum, 
  •  26 September 2023

Effect of lipid‐lowering drugs on renal and cardiovascular outcomes in patients with chronic kidney disease and dyslipidemia: A retrospective cohort study

Yi-Chih Lin MD, MPH, Hsiao-Mei Tsao PhD, Tai-Shuan Lai MD, PhD, Yi-Ting Chen MD, PhD, Yu-Hsiang Chou MD, PhD, Shuei-Liong Lin MD, PhD, Yung-Ming Chen MD, PhD, Kuan-Yu Hung MD, PhD, Yu-Kang Tu DDS, PhD, 
  •  26 September 2023

Utilization of OATP1B Biomarker Coproporphyrin‐I to Guide Drug‐Drug Interaction Risk Assessment: Evaluation by the Pharmaceutical Industry

Ryota Kikuchi, Paresh P. Chothe, Xiaoyan Chu, Felix Huth, Kazuya Ishida, Naoki Ishiguro, Rongrong Jiang, Hong Shen, Simone H. Stahl, Manthena V.S. Varma, Marie-Emilie Willemin, Bridget L. Morse, 
  •  26 September 2023

A Mechanistic‐Physiologically Based Pharmacokinetic Platform Model to Guide Adult and Pediatric Intravenous and Subcutaneous Dosing for Bispecific T Cell Engagers

Xinwen Zhang, Annie Lumen, Hansen Wong, Jamie Connarn, Sandeep Dutta, Vijay V. Upreti, 
  •  25 September 2023
More articles
free access

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

JK Hicks, JR Bishop, K Sangkuhl, DJ Müller, Y Ji, SG Leckband, JS Leeder, RL Graham, DL Chiulli, A LLerena, TC Skaar, SA Scott, JC Stingl, TE Klein, KE Caudle, A Gaedigk, 
  •  127-134
  •  13 May 2015
free access

Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update

Mary V. Relling, Matthias Schwab, Michelle Whirl-Carrillo, Guilherme Suarez-Kurtz, Ching-Hon Pui, Charles M. Stein, Ann M. Moyer, William E. Evans, Teri E. Klein, Federico Guillermo Antillon-Klussmann, Kelly E. Caudle, Motohiro Kato, Allen E.J. Yeoh, Kjeld Schmiegelow, Jun J. Yang, 
  •  1095-1105
  •  17 November 2018
free access

Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update

JK Hicks, K Sangkuhl, JJ Swen, VL Ellingrod, DJ Müller, K Shimoda, JR Bishop, ED Kharasch, TC Skaar, A Gaedigk, HM Dunnenberger, TE Klein, KE Caudle, JC Stingl, 
  •  37-44
  •  20 December 2016
First page image
More articles

CAR T‐cell therapy for multiple myeloma: A clinical practice‐oriented review

Norah Layla Sadek MD, Bruno Almeida Costa MD, Karthik Nath MBBS, PhD, Sham Mailankody MBBS, 

Characterization of the US Food and Drug Administration Post‐Marketing Commitments and Requirements for Pregnancy and Lactation

Charul Avachat, Islam R. Younis, Angela K. Birnbaum, 

Effect of lipid‐lowering drugs on renal and cardiovascular outcomes in patients with chronic kidney disease and dyslipidemia: A retrospective cohort study

Yi-Chih Lin MD, MPH, Hsiao-Mei Tsao PhD, Tai-Shuan Lai MD, PhD, Yi-Ting Chen MD, PhD, Yu-Hsiang Chou MD, PhD, Shuei-Liong Lin MD, PhD, Yung-Ming Chen MD, PhD, Kuan-Yu Hung MD, PhD, Yu-Kang Tu DDS, PhD, 
More articles

Latest news

More news >